American National Bank opened for business in May 1983. The original location was at 10 West Main in what is now known as the Colston building. In January 1984 the home office moved to its present location at 1901 North Commerce.  In June 2016, ANB changed the bank charter from a National charter to a State charter.  The new name, American Nation Bank, was established.

Since the inception of the bank, Jesse Cross has held the position as Chairman of the Board and most of the bank's founders continue as American Nation Bank's directors. Thanks to their strong leadership and progressive ideas, ANB has grown to over $650,000,000 in assets and have ten banking center locations.

ANB acquired two Oklahoma banking centers, the Comanche Banking Center in July 1988, and the Wilson Banking Center in July 1990. Four other Oklahoma additions are the Lone Grove Banking Center opened September 1994, the Homeland Banking Center opened in April 1998, the South Commerce St. Banking Center opened in February 2009, the Durant Banking Center opened in June 2019, and our newest Banking Center in Marietta that opened in May 2022.  In April, 2010 the Texas division, American Bank was transitioned into banking center locations.  This transition added two more locations to serve you; Keller and Saginaw, Texas. All locations are full service and designed to provide quality customer service to all.

American Nation Bank has earned a Five-Star Superior rating from Bauer Financial.  This Five-Star rating is the highest rating and indicates that American Nation Bank is one of the safest in the United States.  Our ratings can be viewed at Bauer Financial ratings board of directors, officers and employees are committed to conservative financial policies and diligent risk management practices, allowing us to offer quality service and high level of financial safety and soundness.  Given our financial strength, strong capital position and because ANB is backed by the full faith and credit of the U.S. Government, you can be sure that your money is safe and secure.